Eyes, taste, muscle, sleep, temperament.

One Val (fast) and one Met (slow) allele. Mid-range prefrontal dopamine.

Val158Met is the famous warrior/worrier SNP. Heterozygotes sit in the middle: more flexible than Met/Met under stress, less dopamine-sticky than Val/Val. This is a temperament tendency, not a diagnosis. rs4633 is also heterozygous; rs6269 is A/A.

Two functional R alleles. Fast-twitch fibers express α-actinin-3. Sprint / strength biased.

The X allele (T) prematurely stops the protein. XX is over-represented in endurance elites; RR is over-represented in power sports. RR is the most common genotype worldwide. It is a training hint: this genome should respond well to heavy resistance and high-intensity intervals. It does not make anyone an athlete by itself.

Bias training toward strength and power if the goal is physique or sport. Endurance is still fully trainable.

Heterozygous for the G allele repeatedly associated with healthy aging in several populations.

FOXO3 is a forkhead transcription factor downstream of insulin/IGF signaling. The G allele of rs2802292 is the most replicated common longevity SNP. Effect is modest and shows up most clearly in centenarian studies. One copy is the common intermediate.

Two Val66 alleles. Typical activity-dependent BDNF secretion.

Met66 (A/T depending on strand) reduces activity-dependent BDNF release and has mixed associations with memory and exercise response. C/C on this chip is Val/Val, the common higher-secretion genotype.

HERC2 rs12913832 G/G almost always means blue irises in European-ancestry people.

This SNP controls an OCA2 enhancer. G/G suppresses OCA2 in the iris. OCA2 rs1800407 is C/C (no brown-restoring Arg419Gln). Combined with European SLC24A5 and SLC45A2, pigmentation is light-European.

Derived light-skin alleles at the two largest-effect loci, plus one TYR S192Y.

SLC24A5 A111 (A/A) and SLC45A2 L374 (G/G) are nearly fixed in Northern Europe. TYR S192Y is heterozygous. MC1R red-hair alleles R151C and R160W are absent. Higher UV vigilance than a deeply pigmented genotype, lower than MC1R red-hair.

Not the East Asian dry-earwax / low-odor allele.

T/T at rs17822931 is the derived East Asian variant (dry cerumen, reduced apocrine odor). C/C is the ancestral wet-earwax type common in Europe and Africa.

One tasting and one non-tasting TAS2R38 haplotype. PTC and similar bitters taste moderately bitter.

The three SNPs form PAV (taster) and AVI (non-taster) haplotypes. Heterozygotes are intermediate. This affects broccoli, kale, coffee, and tonic water more than it affects health.

The C/T soapy-cilantro allele is absent.

rs72921001 C/T near OR6A2 is the most cited cilantro-soap association. A/A is the like-cilantro side of that SNP. Culture and other odorant receptors still matter.

One O deletion and no B-defining allele. Most consistent with A.

rs8176719 D is the O-type single-base deletion; I is A or B. Heterozygous D/I means not group O. rs8176746 G/G is the non-B background used on this chip. rs505922 C (non-O tag) is present once. This is a genetic inference, not a transfusion type — a serology card still wins.

The CHRNA5 D398N and linked CHRNA3 alleles associated with heavier smoking and lung-cancer risk are absent.

These variants increase cigarettes-per-day and lung-cancer risk even after adjusting for smoking quantity. G/G at both is the lower-risk European background. Smoking is still the dominant risk.

CLOCK 3111C, MTNR1B rs10830963 G, and ADA 22G are all absent.

MTNR1B G raises fasting glucose and shifts melatonin signaling — C/C is the easier metabolic genotype. CLOCK 3111C has been tied to delayed sleep; A/A is 3111T/T. ADA 22G can lengthen deep sleep; it is absent. Sleep hygiene still wins.

Heterozygous for a collagen type I variant sometimes tied to lower BMD and soft-tissue injury.

Literature is mixed and effect sizes are small. Worth remembering if there is a fracture or tendon-injury pattern, not worth changing life around.

The low-D2 Taq1A A1 allele is absent. Intermediate C957T.

Taq1A A1 (A) is associated with fewer striatal D2 receptors and a slightly higher addiction vulnerability in some studies. G/G is A2/A2. rs6277 is a synonymous DRD2 SNP with mixed cognitive literature.

One Pro and one Arg at codon 72. Common cosmopolitan genotype.

Arg72 is a bit more apoptotic, Pro72 a bit more cell-cycle arrest, in older literature. Population effects on cancer are small and inconsistent. No action.

A common lower-IL6 promoter genotype and no TNF −308A high-expression allele.

These promoter SNPs have a large, messy literature. They are not clinical tests. The pattern is not a high-inflammatory promoter load.